Syntaxin 1A (Phospho-Ser14) Antibody

Catalog Number:

12059

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q16623;
NCBI Gene#: 6804;
NCBI Protein#: NP_001159375.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of Serine 14 (K-D-S(p)-D-D) derived from Human Syntaxin 1A.

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous level of Syntaxin 1A only when phosphorylated at Serine 14.

Applications:

WB

Background:

Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca2+-regulation of exocytosis acrosomal reaction in sperm.

References:

appl_detail:

Predicted MW: 35kd
Western blotting: 1:500~1:1000

Datasheet PDF