ETS1 (Phospho-Thr38) Antibody

Catalog Number:

11658

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P27577;
NCBI Gene#: 2113;
NCBI Protein#: NP_035938.2.

Form of Antibody:

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of threonine 38(L-L-T(p)-P-S) derived from Human ETS1 .

Purification:

Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Specificity/Sensitivity:

The antibody detects endogenous levels of ETS1 only when phosphorylated at threonine 38.

Applications:

WB IHC IF

Background:

Transcription factor. Directly controls the expression of cytokine and chemokine genes in a wide variety of different cellular contexts. May control the differentiation, survival and proliferation of lymphoid cells. May also regulate angiogenesis through regulation of expression of genes controlling endothelial cell migration and invasion.

Tsukasa Higuchi, Mol. Cell. Biol., May 2007; 27: 3353 - 3366.
NK Bhat, PNAS, May 1990; 87: 3723.
H Suzuki, PNAS, May 1995; 92: 4442.
V Fafeur, Cell Growth Differ., Jun 1997; 8: 655.

References:

appl_detail:

Western blotting: 1:500~1:1000
Immunohistochemistry: 1:50~1:100
Immunofluorescence: 1:100~1:200

Datasheet PDF