Beclin1 (Phospho-Ser30) Antibody

Catalog Number:

11600

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q14457
NCBI Gene ID: 8678
NCBI mRNA#: NM_003766.4
NCBI Protein#: NP_003757.1

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of serine 30 (D-T-S(p)-F-K) derived from Human Beclin1.

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of Beclin1 only when phosphorylated at serine 30.

Applications:

WB IHC IP

Background:

Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration

References:

Xu Qian1,et al. Phosphoglycerate kinase 1 phosphorylates Beclin1 to induce autophagy.Mol Cell. 2017 March 02; 65(5): 917–931.e6. doi:10.1016/j.molcel.2017.01.027. Autho

appl_detail:

 WB dilution: 1:500~1:1000

 IHC dilution: 1:50~1:100

 IP dilution: 1:20~1:50

Datasheet PDF