CDC25A (Phospho-Tyr59) Antibody

Catalog Number:

11598

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P30304
NCBI Gene ID: 993

Form of Antibody:

Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Storage/Stability:

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 59 (S-D-Y(p)-E-Q) derived from Human CDC25A.

Purification:

Specificity/Sensitivity:

The antibody detects endogenous level of cdc25A only when phosphorylated at tyrosine 59.

Applications:

WB IHC

Background:

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.

References:

appl_detail:

Western blotting: 1:500~1:1000

Datasheet PDF