PHOX2B Rabbit mAb

Catalog Number:

78867

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q99453

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human PHOX2B

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome. [provided by RefSeq, Jul 2016]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF