XPD/ERCC2 Rabbit mAb

Catalog Number:

78862

Amount:

100μg

Price:

$318

Swiss-Prot No:

P18074

Form of Antibody:

Storage/Stability:

Immunogen:

Recombinant protein of human XPD/ERCC2.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF