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SPATA18 Antibody

Catalog Number:

25395
other_names: Spermatogenesis associated protein 18, MIEAP, SPETEX1

Amount:

100μg
calculated_mw:
host_species: Chicken

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8TC71
Gene ID:132671

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 19 amino acid peptide near the amino terminus of human SPATA18.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

At least three isoforms of SPATA18 are known to exist; this antibody will detect the two longest isoforms. SPATA18 antibody is predicted to not cross-react with other SPATA family members.

Applications:

ELISA WB

Background:

SPATA18, also known as SPETEX-1, was initially identified as a cytoplasmic protein of elongate spermatids that is thought to be involved in differentiation process of elongate spermatids to mature spermatozoa. Recent experiments have shown that SPATA18 is a transcriptional target of p53 and p63. It has also been suggested to play a role in mitochondria quality control by inducing intramitochondrial lysosome-like organella that eliminate oxidized mitochondrial proteins.

References:

appl_detail:

Datasheet PDF

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