ANKLE1 Antibody

Catalog Number:

25391

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot:Q8NAG6
Gene ID:126549

Form of Antibody:

Supplied in PBS containing 0.02% sodium azide.

Storage/Stability:

Immunogen:

Raised against a 15 amino acid peptide near the carboxy terminus of human ANKLE1.

Purification:

Affinity chromatography purified via peptide column

Specificity/Sensitivity:

Two isoforms of ANKLE1 are known to exist. ANKLE1 antibody is predicted to not cross-react with ANKLE2

Applications:

ELISA WB

Background:

Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. ANKLE1 (Ankyrin repeat and LEM domain containing 1) is a member of ankyrin repeat and LEM domain containing family. It is a potential single-pass membrane protein that contains ankyrin repeats and a Lem domain. Ankyrin repeats mediate protein-protein interactions and are among the most common structural motifs in known proteins. While the function of this protein is still under investigation, its gene locus has been associated with susceptibility to ovarian and breast cancer.

References:

appl_detail:

Datasheet PDF