Cullin 1 Rabbit mAb

Catalog Number:

78286

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q13616

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Cullin 1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

The cullin family proteins are scaffold proteins for the Ring finger type E3 ligases. Humans express seven cullin proeins: CUL1–3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. The Cullin-RING-finger type E3 ligases are important regulators in early embryonic development, as highlighted by genetic studies demonstrating that knock-out of CUL1, CUL3, or CUL4A in mice results in early embryonic lethality.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF