SERCA2/ATP2A2 Rabbit mAb

Catalog Number:

78271

Amount:

100μg

Price:

$318

Swiss-Prot No:

P16615

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human SERCA2/ATP2A2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IP

Background:

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Oct 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IP 1:50 - 1:200

Datasheet PDF