IL17RA Rabbit mAb

Catalog Number:

78254

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q96F46

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human IL17RA

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF