1-832-868-1888
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Catalog Number: |
78227 |
other_names: | ANAPC8, APC8, CUT23 |
Amount: |
100μg |
calculated_mw: | 64kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
Q9UJX2 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human CDC23 |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB,IF |
Background: |
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq, Jul 2008] |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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