MBD3 Rabbit mAb

Catalog Number:

78221

Amount:

100μg

Price:

$318

Swiss-Prot No:

O95983

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human MBD3

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD). The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF