Histone H2A.Z Rabbit mAb

Catalog Number:

78215

Amount:

100μg

Price:

$318

Swiss-Prot No:

P0C0S5

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Histone H2A.Z

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF