[KO Validated] GRK2 Rabbit mAb

Catalog Number:

78202

Amount:

100μg

Price:

$318

Swiss-Prot No:

P25098

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human GRK2

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF