HDAC3 Rabbit mAb

Catalog Number:

78187

Amount:

100μg

Price:

$318

Swiss-Prot No:

O15379

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human HDAC3.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IP

Background:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IP 1:50 - 1:200

Datasheet PDF