1-832-868-1888
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Catalog Number: |
78167 |
other_names: | BDCA4;CD304;NP1;NRP;VEGF165R;Neuropilin-1;NRP1 |
Amount: |
100μg |
calculated_mw: | 120kDa |
host_species: | Rabbit |
Price: |
$318 |
Swiss-Prot No: |
O14786 |
Form of Antibody: |
|
Storage/Stability: |
|
Immunogen: |
A synthesized peptide derived from human Neuropilin-1 (NRP1) (NRP1) |
Purification: |
Affinity purification |
Specificity/Sensitivity: |
|
Applications: |
WB |
Background: |
This gene encodes one of two neuropilins, which contain specific protein domains which allow them to participate in several different types of signaling pathways that control cell migration. Neuropilins contain a large N-terminal extracellular domain, made up of complement-binding, coagulation factor V/VIII, and meprin domains. These proteins also contains a short membrane-spanning domain and a small cytoplasmic domain. Neuropilins bind many ligands and various types of co-receptors; they affect cell survival, migration, and attraction. Some of the ligands and co-receptors bound by neuropilins are vascular endothelial growth factor (VEGF) and semaphorin family members. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2011] |
References: |
|
appl_detail: |
WB 1:500 - 1:2000 |
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