NRAS Rabbit mAb

Catalog Number:

78158

Amount:

100μg

Price:

$318

Swiss-Prot No:

P01111/P01112/P01116_

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human NRAS

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IF

Background:

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]

References:

appl_detail:

WB 1:500 - 1:2000
IF 1:50 - 1:200

Datasheet PDF