CDC25B Rabbit mAb

Catalog Number:

78151

Amount:

100μg

Price:

$318

Swiss-Prot No:

P30305

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human CDC25B

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. [provided by RefSeq, Jul 2008]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF