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Sterol carrier protein 2 Rabbit mAb

Catalog Number:

78101
other_names: SCP2; NLTP; NSL-TP; SCP-2; SCP-CHI; SCP-X; SCPX; sterol carrier protein 2

Amount:

100μg
calculated_mw: 58kDa
host_species: Rabbit

Price:

$318

Swiss-Prot No:

P22307

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Sterol carrier protein 2.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC,IF

Background:

This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200

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