[KO Validated] MyD88 Rabbit mAb

Catalog Number:

78062

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q99836

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human MyD88

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF