CDK5 Rabbit mAb

Catalog Number:

78049

Amount:

100μg

Price:

$318

Swiss-Prot No:

Q00535

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human Cdk5

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a proline-directed serine/threonine kinase that is a member of the cyclin-dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration through phosphorylation of proteins required for cytoskeletal organization, endocytosis and exocytosis, and apoptosis. In humans, an allelic variant of the gene that results in undetectable levels of the protein has been associated with lethal autosomal recessive lissencephaly-7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF