PAI-1/Serpin E1 Rabbit mAb

Catalog Number:

77932

Amount:

100μg

Price:

$318

Swiss-Prot No:

P05121

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human PAI-1/Serpin E1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF