STIP1 Rabbit mAb

Catalog Number:

77907

Amount:

100μg

Price:

$318

Swiss-Prot No:

P31948

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human STIP1

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB,IHC

Background:

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 [PubMed 16100115]).[supplied by OMIM, Jul 2009]

References:

appl_detail:

WB 1:500 - 1:2000
IHC 1:50 - 1:200

Datasheet PDF