CCR2/CKR2 Rabbit mAb

Catalog Number:

77201

Amount:

100μg

Price:

$318

Swiss-Prot No:

P41597

Form of Antibody:

Storage/Stability:

Immunogen:

A synthesized peptide derived from human CCR2/CKR2.

Purification:

Affinity purification

Specificity/Sensitivity:

Applications:

WB

Background:

This gene encodes two isoforms of a receptor for monocyte chemoattractant protein-1, a chemokine which specifically mediates monocyte chemotaxis. Monocyte chemoattractant protein-1 is involved in monocyte infiltration in inflammatory diseases such as rheumatoid arthritis as well as in the inflammatory response against tumors. The receptors encoded by this gene mediate agonist-dependent calcium mobilization and inhibition of adenylyl cyclase. This gene is located in the chemokine receptor gene cluster region. Two alternatively spliced transcript variants are expressed by the gene.

References:

appl_detail:

WB 1:500 - 1:2000

Datasheet PDF