MARK2 Antibody

Catalog Number:

49983

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q7KZI7

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein near the C-terminus of human MARK2.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC,FC

Background:

Microtubule affinity-regulating kinase 2 (MARK2), also known as EMK1 (ELKL motif kinase 1) or Par1b, is a 788 amino acid protein that is a member of the protein kinase superfamily, MARK subfamily. Highly expressed in heart, brain, skeletal muscle and pancreas, MARK2 is essential for the asymmetric development of membrane domains around polarized epithelial cells. Activation of MARK2 by phosphorylation on Thr 208 allows the protein to modulate the building of a columnar versus a hepatic epithelial cell. MARK2 contains one KA1 (kinase-associated) domain, one protein kinase domain and one UBA domain. MARK2 is expressed as 14 isoforms produced by alternative splicing events. Some of these isoforms may function in graft rejection.

References:

appl_detail:

WB: 1:500-1:2,000
IHC: 1:50-1:200


FC: 1:50-1:100

Datasheet PDF