Gemin 1 Antibody

Catalog Number:

49931

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q16637

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within human Gemin 1 aa 1-200.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC,IP

Background:

The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Ensures the correct splicing of U12 intron-containing genes that may be important for normal motor and proprioceptive neurons development. Also required for resolving RNA-DNA hybrids created by RNA polymerase II, that form R-loop in transcription terminal regions, an important step in proper transcription termination. May also play a role in the metabolism of small nucleolar ribonucleoprotein (snoRNPs).

References:

appl_detail:

WB: 1:500-1:1,000
IHC: 1:50-1:200

IP: 1:10-1:50

Datasheet PDF