ADAMTS13 Antibody

Catalog Number:

49953

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#:Q76LX8

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein within human ADAMTS13 aa 150-350.

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC,FC

Background:

ADAMTS13 (a disintegrin and metalloproteinase with a thrombospondin type 1 motif, member 13)also known as von Willebrand factor-cleaving protease (VWFCP)is a zinc-containing metalloprotease enzyme that cleaves von Willebrand factor (vWf), a large protein involved in blood clotting. It is secreted in blood and degrades large vWf multimers, decreasing their activity. Glycosylated. O-fucosylated by POFUT2 on a serine or a threonine residue found within the consensus sequence C1-X2-(S/T)-C2-G of the TSP type-1 repeat domains where C1 and C2 are the first and second cysteine residue of the repeat, respectively. Fucosylated repeats can then be further glycosylated by the addition of a beta-1,3-glucose residue by the glucosyltransferase, B3GALTL.

References:

appl_detail:

WB: 1:500-1:2,000
IHC: 1:50-1:200


FC: 1:50-1:100

Datasheet PDF