1-832-868-1888
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Catalog Number: |
49855 |
other_names: | BLR 1 antibody BLR1 antibody Burkitt lymphoma receptor 1 antibody Burkitt lymphoma receptor 1 GTP binding protein antibody Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5) antibody C |
Amount: |
100μg |
calculated_mw: | 42 kDa |
host_species: | Rabbit |
Price: |
$319 |
Swiss-Prot No: |
Swiss-Prot#:P32302 |
Form of Antibody: |
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Storage/Stability: |
|
Immunogen: |
Recombinant protein |
Purification: |
ProA affinity purified |
Specificity/Sensitivity: |
|
Applications: |
WB,IHC,FC |
Background: |
Burkitt's lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G-protein coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemo-attractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer's patch follicles. BLC expression in Peyer's patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation. |
References: |
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appl_detail: |
WB: 1:500-1:1,000 |
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