SLINGSHOT-1L Antibody

Catalog Number:	48407
other_names:	AW551225 antibody Coro1c antibody coronin, actin binding protein 1C antibody Gm1394 antibody Gm1395 antibody hSSH-1L antibody mSSH 1L antibody OTTMUSP00000031415 antibody Protein phosphatase Slingshot homolog 1 antibody Slingshot 1 antibody slingshot 1L antibody slingshot homolog 1 antibody slingshot like 1 antibody Slingshot1 antibody SSH 1 antibody SSH 1L antibody SSH-1L antibody SSH-like protein 1 antibody Ssh1 antibody SSH1_HUMAN antibody
Amount:	100μg
calculated_mw:	116 kDa
host_species:	Mouse
Price:	$529
Swiss-Prot No:	Swiss-Prot#:Q8WYL5
Form of Antibody:	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Storage/Stability:
Immunogen:	Recombinant protein
Purification:	ProA affinity purified
Specificity/Sensitivity:
Applications:	IHC, FC
Background:	Slingshot homolog (SSH) family of phosphatases, which regulate actin filament dynamics. The SSH proteins dephosphorylate and activate the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Cofilin is inactivated by kinases such as LIM domain kinase-1 (LIMK1), which may also be dephosphorylated and inactivated by SSH proteins. The SSH family thus appears to play a role in actin dynamics by reactivating cofilin proteins. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
References:
appl_detail:	IHC: 1:50-1:200 FC: 1:50-1:100
	Datasheet PDF

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