CUB domain-containing protein 1 Antibody

Catalog Number:

48377

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:Q9H5V8

Form of Antibody:

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein.

Purification:

Protein affinity purified

Specificity/Sensitivity:

Applications:

WB,IHC,ICC

Background:

CDCP1 (CUB-domain-containing protein 1) contains three extracellular CUB domains, a transmembrane domain, and two putative cytoplasmic tyrosine phosphorylation sites. Phosphorylation of the gp140 and p80 proteins is mediated by Src family kinases at various tyrosine residues, including Tyr 734. PTP family members mediate the desphosphorylation of CDCP1. The conversion of gp140 to p80 prolongs the phosphorylation state, which may affect signaling in epithelial wounds. CDCP1 acts as a marker for hematopoetic cells and also exhibits high expression in metastatic colon and breast tumors.

References:

appl_detail:

WB: 1:500
IHC: 1:50-1:100
ICC: 1:50

Datasheet PDF