1-832-868-1888
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Catalog Number: |
48121 |
other_names: | 116 kDa antibody 116 kDa U5 small nuclear ribonucleoprotein component antibody EFTUD2 antibody Elongation factor Tu GTP binding domain containing 2 antibody Elongation factor Tu GTP-binding domain-containing protein 2 antibody hSNU114 antibody MFDGA antibody MFDM antibody SNRNP116 antibody Snrp116 antibody Snu114 antibody SNU114 homolog antibody U5 116KD antibody U5 small nuclear ribonucleoprotein component antibody U5 snRNP specific protein, 116 kD antibody U5 snRNP specific protein, 116 kDa antibody U5 snRNP-specific protein antibody U5-116 kDa antibody U5-116KD antibody U5S1_HUMAN antibody |
Amount: |
100μg |
calculated_mw: | 116 kDa |
host_species: | Mouse |
Price: |
$529 |
Swiss-Prot No: |
Swiss-Prot#:O08810 |
Form of Antibody: |
1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Storage/Stability: |
|
Immunogen: |
peptide |
Purification: |
ProA affinity purified |
Specificity/Sensitivity: |
|
Applications: |
WB, ICC, IHC, FC |
Background: |
Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA. Snrp116, also known as EFTUD2 (elongation factor Tu GTP binding domain containing 2) or Snu114, is a 972 amino acid protein that localizes to the nucleus and belongs to the GTP-binding elongation factor family. Existing as a component of the multi-protein U5 snRNP spliceosome complex, Snrp116 plays an important role in pre-mRNA splicing, as well as in the recycling of spliceosomal snRNPs. The gene encoding Snrp116 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. |
References: |
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appl_detail: |
WB: 1:1,000-1:2,000 |
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