Alpha smooth muscle Actin Antibody

Catalog Number:

48104

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:P62736

Form of Antibody:

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

This antibody is produced by immunizing mice with a synthetic peptide (KLH-coupled) corresponding to a region of alpha smooth muscle Actin.

Purification:

ProG affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC, IHC, FC

Background:

Actins are highly conserved proteins involved in cell motility, structure and integrity. Actin has been found to be expressed in at least six isomeric forms. It is expressed in heart and skeletal striated muscle tissue, and in certain smooth muscle tissues, regulating contractile potentials for these cells. It is also expressed in the cytoplasm of non-muscle cells, functioning to control cell structure and motility. Smooth muscle alpha actin is of further interest because it is one of a few genes whose expression is relatively restricted to vascular smooth muscle cells. Expression of smooth muscle alpha actin is regulated by hormones, cell proliferation, and altered by pathological conditions including oncogenic transformation and atherosclerosis.

References:

appl_detail:

WB: 1:1,000
IHC: 1:200
ICC: 1:200

Datasheet PDF