C14orf93 Antibody

Catalog Number:

48082

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#:Q9H972

Form of Antibody:

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

Storage/Stability:

Immunogen:

Recombinant protein

Purification:

ProA affinity purified

Specificity/Sensitivity:

Applications:

WB, ICC, IHC, FC

Background:

C14orf93 (also named as Regulator of Thyroid Function and Cancer, RTFC) as a novel susceptibility gene for familial nonmedullary thyroid cancer.The oncogenic functions of R115Q, V205M, and G209D RTFC mutants are demonstrated by cell surviving assay, migration assay, and colony forming assays. Moreover, RTFC has been identified as a potential antigen associated with the pathogenesis of peripheral T-cell lymphomas, not otherwise specified (PTCL, NOS). Two in vitro biochemical screens suggested that RTFC might have RNA and phosphopeptide (pSer/pThr-X-X-X-pSer/pThr) binding activities. Yet, the role of RTFC in normal development, as well as the molecular function of RTFC, remain unexplored.

References:

appl_detail:

WB: 1:500-1:1,000
IHC: 1:50-1:200
ICC: 1:50-1:200

FC: 1:50-1:200

Datasheet PDF