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LILRB5 Antibody

Catalog Number:

43739
other_names: LIR8; CD85C; LIR-8

Amount:

100μg
calculated_mw: 64kd
host_species: Rabbit

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O75023
NCBI Gene ID: 10990

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human LILRB5

Purification:

Antigen affinity purification

Specificity/Sensitivity:

The antibody detects endogenous levels of total LILRB5 protein.

Applications:

IHC WB

Background:

This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene.

References:

appl_detail:

Western blotting: 1:200-1000
Immunohistochemistry: 1: 20-100

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