1-832-868-1888
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Catalog Number: |
42048 |
other_names: | Timp-1 |
Amount: |
100μg |
calculated_mw: | |
host_species: | Mouse |
Price: |
$529 |
Swiss-Prot No: |
Swiss-Prot#: P30120 |
Form of Antibody: |
Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Storage/Stability: |
|
Immunogen: |
Recombinant Rat Timp1 |
Purification: |
protein G purifed |
Specificity/Sensitivity: |
specific for Rat Timp1 denatured and native forms |
Applications: |
IHC |
Background: |
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also stimulates steroidogenesis by Leydig and ovarian granuloma cells; procathepsin L is required for maximal activity. |
References: |
[1] "Cloning of the cDNA encoding rat tissue inhibitor of metalloproteinase 1 (TIMP-1), amino acid comparison with other TIMPs, and gene expression in rat tissues." [2] Gibbons K.L., O'Grady R.L., Piper A.A. "Analysis of the cDNA encod |
appl_detail: |
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