Timp1 Monoclonal Antibody

Catalog Number:

42030

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#: P01033

Form of Antibody:

Preservative: 15mmol/L NaN3Constituents: 0.1mol/L Nacl, 50% glycerol

Storage/Stability:

Immunogen:

human Timp 1

Purification:

protein G purifed

Specificity/Sensitivity:

specific for Human Timp1 denatured and native forms

Applications:

WB

Background:

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

References:

[1] Docherty A.J.P., Lyons A., Smith B.J., Wright E.M., Stephens P.E., Harris T.J.R.,Murphy G., Reynolds J.J.Sequence of human tissue inhibitor of metalloproteinases and its identity to erythroid-potentiating activity. Nature 318:66-69(1985) [2] Gasson

appl_detail:

Western blotting: 1:500 - 1:1000
Immunohistochemistry: 1:20 - 1:200

Datasheet PDF