Nestin Monoclonal Antibody

Catalog Number:

42024

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#: P48681

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant nestin Protein

Purification:

protein G purifed

Specificity/Sensitivity:

specific for Human Nestin denatured and native forms

Applications:

IHC

Background:

Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells.

References:

[1] Dahlstrand J., McKay R.D.G., Zimmerman L.B., Lendahl U.Characterization of the human nestin gene reveals a close evolutionary relationship to neurofilaments.J. Cell Sci.1992.103;589-597.[2]Gregory S.G., Barlow K.F., McLay K.E., Kaul R., Swarbreck D.,

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF