GAL-3 Monoclonal Antibody

Catalog Number:

42023

Amount:

100μg

Price:

$529

Swiss-Prot No:

Swiss-Prot#: P17931

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant Human Galectin 3(GAL-3)

Purification:

protein G purifed

Specificity/Sensitivity:

specific for human Galectin 3(GAL-3) denatured and native forms

Applications:

IHC

Background:

Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis By similarity. In the nucleus: acts as a pre-mRNA splicing factor. Involved in acute inflammatory responses including neutrophil activation and adhesion, chemoattraction of monocytes macrophages, opsonization of apoptotic neutrophils, and activation of mast cells.

References:

[1] Robertson M.W., Albrandt K., Keller D., Liu F.-T. Human IgE-binding protein: a soluble lectin exhibiting a highly conserved interspecies sequence and differential recognition of IgE glycoforms. Biochemistry 29:8093-8100(1990) [2] Cherayil B., Chaitov

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF