SPINK7 Antibody

Catalog Number:

43262

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P58062
Gene ID: 84651

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Synthetic peptide of human SPINK7

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SPINK7 protein.

Applications:

IHC

Background:

SPINK7 (serine peptidase inhibitor, Kazal type 7), also known as Ecg2 (esophagus cancer-related gene 2 protein), is a 76 amino acid secreted protein. Containing one Kazal-like domain, SPINK7 is thought to be a serine protease inhibitor. The gene that encodes SPINK7 maps to human chromosome 5, which contains 181 million base pairs encoding around 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.Probable serine protease inhibitor.

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF