TWSG1 Antibody

Catalog Number:

42983

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q9GZX9
Gene ID: 57045

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Fusion protein of human TWSG1

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total TWSG1 protein.

Applications:

IHC

Background:

May be involved in dorsoventral axis formation. Seems to antagonize BMP signaling by forming ternary complexes with CHRD and BMPs, thereby preventing BMPs from binding to their receptors. In addition to the anti-BMP function, also has pro-BMP activity, partly mediated by cleavage and degradation of CHRD, which releases BMPs from ternary complexes. May be an important modulator of BMP-regulated cartilage development and chondrocyte differentiation. May play a role in thymocyte development (By similarity).

References:

appl_detail:

Immunohistochemistry: 1:25-1:100

Datasheet PDF