SESN3 Antibody

Catalog Number:

42754

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P58005
Gene ID: 143686

Form of Antibody:

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Storage/Stability:

Immunogen:

Full length fusion protein of human SESN3

Purification:

Antigen affinity purification.

Specificity/Sensitivity:

The antibody detects endogenous levels of total SESN3 protein.

Applications:

IHC

Background:

This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants.

References:

appl_detail:

Immunohistochemistry: 1:100-1:200

Datasheet PDF