Serpin B3 Polyclonal Antibody

Catalog Number:

42534

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P29508

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Serpin B3 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Serpin B3 polyclonal antibody.

Applications:

IHC

Background:

May act as a papain-like cysteine protease inhibitor to modulate the host immune response against tumor cells. Also functions as an inhibitor of UV-induced apoptosis via suppression of the activity of c-Jun NH(2)-terminal kinase (JNK1).

References:

[1]"Increased antiprotease activity of the SERPINB3 polymorphic variant SCCA-PD."Turato C., Biasiolo A., Pengo P., Frecer V., Quarta S., Fasolato S., Ruvoletto M., Beneduce L., Zuin J., Fassina G., Gatta A., Pontisso P.Exp. Biol. Med. 236:281-290(2011).

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF