Nuclear factor NF-kappa-B p105 subunit 1 Polyclonal Antibody

Catalog Number:

42522

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P19838

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Nuclear factor NF-kappa-B p105 subunit protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Nuclear factor NF-kappa-B p105 subunit 1 polyclonal antibody.

Applications:

WB

Background:

NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one.

References:

[1] "The DNA binding subunit of NF-kappa B is identical to factor KBF1 and homologous to the rel oncogene product."Kieran M., Blank V., Logeat F., Vandekerckhove J., Lottspeich F., le Bail O., Urban M.B., Kourilsky P., Baeuerle P.A., Israel A.Cell 62:1007

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF