Substance-P receptor Polyclonal Antibody

Catalog Number:

42508

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P25103

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Substance-P receptor protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Substance-P receptor polyclonal antibody.

Applications:

IHC

Background:

This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.

References:

[1] "Molecular cloning, structural characterization and functional expression of the human substance P receptor."Takeda Y., Chou K.B., Takeda J., Sachais B.S., Krause J.E.Biochem. Biophys. Res. Commun. 179:1232-1240(1991) [2] "Isolation and characteris

appl_detail:

Immunohistochemistry: 1:20 - 1:200

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