Actin-related protein 2/3 complex subunit 3 Polyclonal Antibody

Catalog Number:

42389

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: O15145

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Actin-related protein 2/3 complex subunit 3 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Actin-related protein 2/3 complex subunit 3 polyclonal antibody.

Applications:

WB

Background:

p21-ARC is part of a complex implicated in the control of actin polymerization in cells. It belongs to a complex composed of ARP2, ARP3, ARPC1, ARPC2, ARPC3, ARPC4 and ARPC5, collectively known as the ARPC3 family. p21-ARC is implicated as an important regulator of growth cone translocation, especially in the CNS (Strasser et al, 2004).

References:

[1] "Mammalian actin-related protein 2/3 complex localizes to regions of lamellipodial protrusion and is composed of evolutionarily conserved proteins."Machesky L.M., Reeves E., Wientjes F., Mattheyse F.J., Grogan A., Totty N.F., Burlingame A.L., Hsuan J.

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF