Prefoldin subunit 5 Polyclonal Antibody

Catalog Number:

42255

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: Q99471

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Prefoldin subunit 5 protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Prefoldin subunit 5 polyclonal antibody.

Applications:

IHC

Background:

Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.Heterohexamer of two PFD-alpha type and four PFD-beta type subunits. Binds to MYC; interacts with its N-terminal domain. Represses the transcriptional activity of MYC.Highly expressed in pancreas and skeletal muscle and moderately in other tissues.Belongs to the prefoldin subunit alpha family.

References:

[1]"MM-1, a novel c-Myc-associating protein that represses transcriptional activity of c-Myc." Mori K., Maeda Y., Kitaura H., Taira T., Iguchi-Ariga S.M., Ariga H. J. Biol. Chem. 273:29794-29800(1998) [2]"MM-1, a c-Myc-binding protein, is a candidate

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF