Lysosomal acid lipase/cholesteryl ester hydrolase Polyclonal Antibody

Catalog Number:

42238

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P38571

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Lysosomal acid lipase/cholesteryl ester hydrolase protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Lysosomal acid lipase/cholesteryl ester hydrolase polyclonal antibody.

Applications:

WB

Background:

Crucial for the intracellular hydrolysis of cholesteryl esters and triglycerides that have been internalized via receptor-mediated endocytosis of lipoprotein particles. Important in mediating the effect of LDL (low density lipoprotein) uptake on suppression of hydroxymethylglutaryl-CoA reductase and activation of endogenous cellular cholesteryl ester formation.

References:

[1]Cloning and expression of cDNA encoding human lysosomal acid lipase/cholesteryl ester hydrolase. Similarities to gastric and lingual lipases.Anderson R.A., Sando G.N.J. Biol. Chem. 266:22479-22484(1991) [2]Purification, characterization and molecular

appl_detail:

Western blotting: 1:500 - 1:1000

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