Keratin, type I cytoskeletal 14 Polyclonal Antibody

Catalog Number:

42234

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P02533

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant human Keratin, type I cytoskeletal 14 protein£¨1-472aa£©

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Keratin, type I cytoskeletal 14 polyclonal antibody.

Applications:

IHC

Background:

The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro.

References:

[1]"Novel and recurrent mutations in keratin KRT5 and KRT14 genes in epidermolysis bullosa simplex: implications for disease phenotype and keratin filament assembly." Mueller F.B., Kuester W., Wodecki K., Almeida H. Jr., Bruckner-Tuderman L., Krieg T., Ko

appl_detail:

Immunohistochemistry: 1:20 - 1:200

Datasheet PDF