Plasma kallikrein Polyclonal Antibody

Catalog Number:

42232

Amount:

100μg

Price:

$319

Swiss-Prot No:

Swiss-Prot#: P14272

Form of Antibody:

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Storage/Stability:

Immunogen:

Recombinant Rat Plasma kallikrein protein

Purification:

Caprylic Acid Ammonium Sulfate Precipitation purified

Specificity/Sensitivity:

The antibody detects endogenous level of total Plasma kallikrein polyclonal antibody.

Applications:

WB

Background:

The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin.

References:

[1]Gene structure and chromosomal localization of plasma kallikrein.Beaubien G., Rosinski-Chupin I., Mattei M.-G., Mbikay M., Chretien M., Seidah N.G. Biochemistry 30:1628-1635(1991) [2] The cDNA structure of rat plasma kallikrein.Seidah N.G., Ladenheim

appl_detail:

Western blotting: 1:500 - 1:1000

Datasheet PDF